Using Genetically Encoded Calcium Indicators to Study Astrocyte Physiology: A Field Guide

Lohr, Christian and Beiersdorfer, Antonia and Fischer, Timo and Hirnet, Daniela and Rotermund, Natalie and Sauer, Jessica and Schulz, Kristina and Gee, Christine E. (2021) Using Genetically Encoded Calcium Indicators to Study Astrocyte Physiology: A Field Guide. Frontiers in Cellular Neuroscience, 15. ISSN 1662-5102

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Official URL: https://doi.org/10.3389/fncel.2021.690147

Abstract

Ca2+ imaging is the most frequently used technique to study glial cell physiology. While chemical Ca2+ indicators served to visualize and measure changes in glial cell cytosolic Ca2+ concentration for several decades, genetically encoded Ca2+ indicators (GECIs) have become state of the art in recent years. Great improvements have been made since the development of the first GECI and a large number of GECIs with different physical properties exist, rendering it difficult to select the optimal Ca2+ indicator. This review discusses some of the most frequently used GECIs and their suitability for glial cell research.

Item Type:	Article
Subjects:	Article Archives > Medical Science
Depositing User:	Unnamed user with email support@articlearchives.org
Date Deposited:	14 Apr 2023 05:48
Last Modified:	26 Jul 2024 06:30
URI:	http://archive.paparesearch.co.in/id/eprint/1024

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